TLDR
- ARK Innovation ETF sold 21,592 Roku shares worth $2.12 million on September 25, 2025
- ARK dumped 10,667 Roblox shares valued at $1.42 million from the same fund
- ARK Genomic ETF purchased 26,536 Arcturus Therapeutics shares for $542,661
- Roku maintains position as ARK’s third-largest holding with 4.66% portfolio weight
- Arcturus receives “Strong Buy” rating from analysts with 198% upside potential
Cathie Wood’s ARK Investment Management executed a strategic portfolio rebalancing on September 25, 2025, selling streaming and gaming positions while increasing biotech exposure. The moves totaled over $3.5 million in transactions across ARK’s flagship funds.
The ARK Innovation ETF (ARKK) led the trading activity with its largest single transaction of the day. The fund sold 21,592 shares of streaming platform Roku Inc (NASDAQ: ROKU) for $2.12 million.
ARK simultaneously reduced its gaming exposure by selling 10,667 shares of Roblox Corp (NYSE: RBLX) worth $1.42 million. The Roblox sale continues a pattern from earlier in the week when ARK sold $2.71 million worth of the gaming platform’s stock.
Both companies have delivered strong returns in 2025. Roku shares have climbed nearly 32% year-to-date, while Roblox has surged an impressive 128%.
Despite recent sales, Roku remains a core ARK holding. The streaming company maintains its position as the third-largest holding across ARK’s combined portfolios with a 4.66% weighting.
ARK Increases Biotech Bet on RNA Medicine
While reducing tech positions, ARK’s Genomic Revolution ETF (ARKG) added 26,536 shares of Arcturus Therapeutics Holdings Inc (NASDAQ: ARCT). The biotech purchase was valued at $542,661.
The Arcturus acquisition extends ARK’s recent buying pattern in the stock. Wood’s team has accumulated shares of the RNA medicine company across multiple trading sessions over the past week.
Wall Street analysts currently rate Arcturus as a “Strong Buy” with consensus price targets suggesting 198% upside potential over the next 12 months. The company specializes in RNA medicines and vaccine technologies.
Strategic Shift Toward High-Growth Sectors
The September 25 trades reflect smaller dollar amounts compared to Wood’s typical portfolio moves. This measured approach comes during heightened market volatility, particularly affecting technology stocks.
Wood appears to be reallocating capital from consumer-focused technology companies toward sectors with higher perceived growth potential. These target areas include biotechnology, artificial intelligence, and cryptocurrency-related investments.
ARK’s trading activity provides transparency into one of the market’s most closely watched investment strategies. Wood’s focus on disruptive innovation drives the fund’s active management philosophy.
The latest portfolio adjustments were disclosed in ARK’s daily trading reports for September 25, 2025.
