TLDR
- Ethereum surged over 2% above $4,600 following the Federal Reserve’s 25 basis point rate cut
- Mid-sized whale wallets reached unrealized profit levels matching November 2021 market peak
- Major whale transactions included 100,000 ETH sold worth millions and single 5,000 ETH dump for $22.84 million
- Ethereum ETF outflows totaled $1.89 million despite positive Fed policy changes
- Price targets range from $4,000 correction to potential $5,000+ rally depending on key resistance breaks
Ethereum’s price action on September 19, 2025, reflects the complex dynamics between Federal Reserve policy support and large holder profit-taking behavior. The second-largest cryptocurrency by market capitalization climbed above $4,600 in direct response to the Fed’s dovish monetary policy decision.

The 25 basis point interest rate reduction provided immediate bullish momentum for Ethereum price. ETH successfully broke through the $4,550 resistance level and established support above $4,500. Trading activity increased over 35% as the token reached a 24-hour high of $4,643.
Ethereum’s technical structure shows a recovery wave forming above the critical $4,420 base level. The price action mirrors Bitcoin’s recent strength, with both assets benefiting from improved macroeconomic conditions. ETH now trades above its 100-hourly Simple Moving Average, indicating short-term bullish momentum.
Key resistance levels remain at $4,640 and $4,685, with the major resistance target sitting at $4,765. A successful break above $4,765 could trigger further upside toward $4,840, potentially extending to $4,880 or $4,920 in optimistic scenarios.
Whale Activity Creates Market Uncertainty
On-chain data reveals concerning patterns in large holder behavior that could impact Ethereum’s price trajectory. Mid-sized whales holding between 10,000 and 100,000 ETH have reached unrealized profit levels not seen since the November 2021 all-time high period.

This profit accumulation has historically preceded selling pressure from large holders. Recent whale activity confirms this pattern, with 90,000 ETH worth approximately $500 million sold over two trading sessions. One individual whale transaction moved 5,000 ETH to Binance exchange for $22.84 million, generating $5.08 million in realized profits.
The concentration of profit-taking among whales creates downside pressure that could counteract Federal Reserve policy benefits. Historical precedent suggests that similar whale profit conditions in 2021 preceded market corrections.
Institutional Flows Show Mixed Signals
Ethereum exchange-traded fund flows present conflicting narratives about institutional demand. Despite the Federal Reserve’s accommodative policy stance, spot Ethereum ETFs recorded net outflows of $1.89 million on September 18.
Fidelity’s FETH product experienced the largest outflow at $29.19 million, while Bitwise’s ETHW recorded $9.7 million in redemptions. These outflows occurred after BlackRock and Fidelity had already sold $68.40 million in ETH holdings earlier in the week.
Traditional financial institutions maintain divergent Ethereum price predictions for year-end 2025. Citigroup projects a conservative $4,300 target, with downside scenarios reaching $2,200. Conversely, Standard Chartered maintains bullish expectations above $5,000, with Citigroup’s optimistic case targeting $6,400.
Ethereum Price Prediction
Technical analysis from multiple analysts suggests Ethereum faces critical resistance levels that will determine near-term price direction. Popular trader Michael van de Poppe maintains that ETH holds above crucial support areas, but warns of potential drops below $4,000 if these levels fail.
Analyst Ted Pillows identifies consolidation below $4,700 resistance as a key concern. His analysis suggests failure to break current resistance could trigger declines toward $4,000. The TD Sequential indicator has flashed sell signals according to analyst Ali Martinez, targeting a retest of $4,570.
Support levels for potential corrections include $4,580, $4,535, and $4,465. A break below $4,535 could accelerate selling toward $4,420 or even $4,350. Current price action at $4,580 represents a 2% daily gain, but faces the challenge of overcoming whale profit-taking and institutional hesitation.